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Comparing two different doses of bupivacaine in epidural volume extension

Comparison of intrathecal doses of plain bupivacaine for epidural volume extension induced sensory block augmentation: a randomised controlled double-blinded trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/12/007606
Enrollment
84
Registered
2016-12-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- male patients undergoing Orthopedic lower limb surgery

Interventions

Intervention1: Epidural volume Extension: Epidural volume Extension will be performed by injecting 10ml normal saline in epidural space Intervention2: PE5 (plain bupivacaine 5mg with epidural volume e

Sponsors

University College of Medical Sciences and Guru Teg Bahadur Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA status I or II with body weight between 50-70 kg and height of 150-180 cm undergoing lower limb surgery using combined spinal epidural technique.

Exclusion criteria

Exclusion criteria: Patients with diabetes mellitus, history of spinal disease or coagulation abnormalities, skin infection at site of injection and other contraindications to combined spinal epidural anesthesia including hypersensitivity to local anesthetics

Design outcomes

Primary

MeasureTime frame
The maximum sensory block level (Smax) achievedTimepoint: The sensory blockade will be assessed every 3 min till there is no further increase in 3 consecutive readings. This level of sensory blockade will be designated as maximum level of sensory block (Smax).

Secondary

MeasureTime frame
The increase in maximum sensory block level caused by epidural volume extensionTimepoint: The sensory blockade will be assessed every 3 min till there is no further increase in 3 consecutive readings. This level of sensory blockade will be designated as maximum level of sensory block (Smax).

Countries

India

Contacts

Public ContactMukundan Ramanujam

University College of Medical Sciences and Guru Teg Bahadur Hospital

iammukundan@gmail.com9789306906

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026