Health Condition 1: null- PATEINTS WITH LOCALLY ADVANCED NON METASTATIC THYROID CANCER IN GOOD GENERAL CONDITION
Conditions
Interventions
Intervention1: Radiation therapy: patients will receive surgery followed by radioiodine therapy followed by external beam radiation therapy (IMRT)
THE TOTAL DURATION OF THERAPY- 6-8 WEEKS
Control Inte
Sponsors
Tata Memorial Hospital Intramural fundin
Eligibility
Inclusion criteria
Inclusion criteria: A) All patients of thyroid cancer (papillary/follicular/poorly differentiated) who have undergone total/completion thyroidectomy at our institute and having at least two of the following features (listed below) intra-operatively and/or on histopathology 1. Gross extrathyroidal spread into soft tissues of the neck, trachea, esophagus, recurrent laryngeal nerve (constituting stage T4a) 2. R1/ shave resections (minimal residual disease) 3. R2 resections (gross residual disease) 4. Multiple lymph nodes positive( >2) with perinodal extension at level VI B) Normal baseline haematological and biochemical parameters
Exclusion criteria
Exclusion criteria: 1. Anaplastic or medullary thyroid cancer 2. Previous history of radiation 3. Pregnancy 4. 5. Patient unwilling to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â?¢ To assess the impact of adjuvant RT on loco-regional control in patients with locally advanced differentiated thyroid cancers who have undergone surgery with radioiodine therapyTimepoint: â?¢ Assessment for locoregional recurrence will be done at every follow up upto five years after completion of treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ To assess toxicity (early and late at 2 years) of adjuvant RT in these patientsTimepoint: at 2 years | — |
Countries
India
Contacts
Public ContactDR GOURI PANTVAIDYA
TATA MEMORIAL HOSPITAL
Outcome results
None listed