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Clinical trial to study the effect of continuous infusion of local anesthetic drugs in providing pain relief after abdominal surgery

Efficacy of continuous wound infusion of local anaesthetic after laparotomy; a prospective, double blind, randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/12/007583
Enrollment
94
Registered
2016-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Adult patients without any liver and renal dysfunction, and hypersensitivity to local anesthetic drug bupivacaine, undergoing elective midline laparotomy.

Interventions

Intervention1: Bupivacaine (0.25%): Bupivacaine 0.25%, will be administered continuously into the laparotomy wound in the pre-peritoneal plane at a rate of 6 ml/ hr, for a duration of 48 hours Dose:

Sponsors

Jawaharlal Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients undergoing elective abdominal surgery via a midline laparotomy incision and not requiring creation of stoma.

Exclusion criteria

Exclusion criteria: 1. Impaired renal function 2. Impaired liver function 3. Presence of psychiatric illness 4. Chronic analgesic intake 5. Allergy to bupivacaine

Design outcomes

Primary

MeasureTime frame
1. Amount of morphine consumed (in mg)Timepoint: 24 hours and 48 hours postoperatively

Secondary

MeasureTime frame
1. Pain scores using Visual Analogue Scale 2. Peak Expiratory Flow Rate 3. Postoperative nausea and vomiting 4. Time to passage of first flatusTimepoint: 24 hours and 48 hours postoperatively

Countries

India

Contacts

Public ContactBaskaran D

Department of General Surgery, JIPMER

sarathsistla@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026