A clinical trial to compare the effect of two group of drugs while giving anesthesia in patients posted for major surgeries.

Comparison of hemodynamic effects and ease of I-gel insertion with dexmedetomidine propofol vs fentanyl propofol

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/12/007572

Enrollment

Registered

2016-12-14

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA 1 and ASA 2 patients posted for surgery

Interventions

Intervention1: Intervention : Propfol : Dose : 2 mg per kg one dose Route : Intravenous used for induction Control Intervention1: Comparator A : Dexmedetomidine: Dose : 2 mcg per kg one dose Route :

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I & II. 2. 18-60 years of age. 3. Weight 35-80kgs. 4. Who gives informed written consent. 5. Patients scheduled to undergo elective surgical procedures .

Exclusion criteria

Exclusion criteria: 1. Risk of gastric aspiration. 2. Patient who refuse for the study or have any known allergy. 3. Patients undergoing oral surgeries. 4. Those with Hepatic/ Renal/cardio-pulmonary abnormality, bleeding diathesis. 5. ASA grade III & IV patients.

Design outcomes

Primary

Measure	Time frame
â?¢ Heart rate, Respiratory rate ,Non invasive blood pressure and Oxygen saturation will be recorded before inductionTimepoint: Baseline, 30sec after induction, 1min, 3min,5min,10min and 15min after insertion of I-gel	—

Secondary

Measure	Time frame
jaw mobility and coughing / buckingTimepoint: 2 optimum for i gel insertion	—

Countries

India

Contacts

Public ContactDr Priyanka Dabas

Kasturba Medical College, Mangalore

dr_jitesh@yahoo.co.in9845107528

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026