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Lowest Concentration of Ropivacaine(Local Anaesthetic) needed for lower leg anaesthesia

Minimum Effective Anaesthetic Concentration(MEAC90) of Ropivacaine in Ultrasound Guided Popliteal Sciatic Nerve Block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/12/007563
Enrollment
45
Registered
2016-12-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Surgeries Involving unilateral leg of less than 2 hours duration

Interventions

Intervention1: Ropivacaine: A single dose of 20 ml ropivacaine is used to block the sciatic nerve at popliteal level. The drug will be injected perineurally. The concentration of drug used will be ser

Sponsors

Jubilee Mission Medical College and Research Institute
Lead Sponsor
Dr Sahir Aftab
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for unilateral leg surgeries of less than 2 hours duration. Only ASA physical status 1 and 2 patients are studied.

Exclusion criteria

Exclusion criteria: Infection at site of injection Deranged renal and hepatic function Allergic to ropivacaine Peripheral neuropathy involving leg

Design outcomes

Primary

MeasureTime frame
To find out the minimum effective anaesthetic concentration of ropivacaine required for ultrasound guided popliteal sciatic nerve block in 90% of the population (MEAC90).Timepoint: Assessed by sensory blockade within 30 minutes of injection—

Secondary

MeasureTime frame
Duration of analgesia following injectionTimepoint: assessed by time to first analgesic request following blockade till 24 hours after block;Find the time required for onset of anaesthesiaTimepoint: Assessed every 5 minutes after injection up to 30 minutes—

Countries

India

Contacts

Public ContactDr Sahir Aftab

Jubilee Mission Medical College and Research Institute

sahir.aftab@gmail.com919995343524

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026