Skip to content

To measure effect of low dose aspirin in patient undergoing routine dental extraction such as increase bleeding or not.

Effect of low dose aspirin on bleeding following exodontia: A prospective clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2016/12/007550
Enrollment
100
Registered
2016-12-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients withcardiovascular or peripheral venous disease who are on low dose aspirin ranging from 75-150mg requiring routine dental extractions.

Interventions

Intervention1: nil: nil

Sponsors

Bharati Vidyapeeth Deemed University Dental College And HospitalPune
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient on long term low dose single anti-platelet therapy aspirin (75 to 150mg). 2.Patients with PT- INR less than 1.5. 3.Patients between 30-60 years of age. 4.Patients without any bleeding disorders. 5.Not allergic to the drugs or anesthetic agent being used. 6.Patients willing to participate in study. 7.Patient with fitness obtained from physician to undergo exodontia.

Exclusion criteria

Exclusion criteria: 1)Patients on aspirin therapy >150mg/day. 2) Patients INR >3.5. 3)Pregnant or lactating women. 4)Patients with hepatic, renal diseases or epilepsy or with a clinical history of debilitating respiratory diseases. 6)Patients with bleeding or clotting disorders. 7)Patients belonging to ASA Grade III, IV, V. 8)Procedure under General Anesthesia or Conscious sedation.

Design outcomes

Primary

MeasureTime frame
Perioperative blood loss was measured for each extraction by swab weighing method both in test group and control group.Number of gauze used and time of bleeding (early, immediate or late) postoperatively.The patients were checked after 24 hours, 48 hours,72 hours and 1 week, and bleeding complaints were recorded.Use of local haemostatic agrnts like sutures, gel foam, tranexamic acid, botroclot, electrocautery were also assessed at different time intervals after exodontia.Timepoint: Bleeding is measured quantatively by gauze weighing method intraopeartively and qualitatively after interval of 30mins,24hrs, 48 hrs,72 hrs and 1week postoperatively.

Secondary

MeasureTime frame
Postoperative bleeding if any after 1 week and need for fresh frozen plasma transfusion if bleeding continues after 1week.Timepoint: 1week

Countries

India

Contacts

Public ContactDr Rohan Gupta Dr Arun Dugal

Bharati vidyapeeth deemed university dental college and hospital,Pune

dugalag@yahoo.co.in9822058244

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026