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COMPARISION OF EFFICACY AND SAFETY OF BUPRENORPHINE AND BUTORPHANOL AS ADJUVANT TO LEVOBUPIVACAINE IN ULTRASOUND GUIDED AXILLARY BRACHIAL PLEXUS BLOCK

A COMPARATIVE STUDY OF EFFICACY AND SAFETY OF BUPRENORPHINE AND BUTORPHANOL AS ADJUVANT TO 0.375% LEVOBUPIVACAINE IN ULTRASOUND GUIDED AXILLARY BRACHIAL PLEXUS BLOCK- A RANDOMIZED CONTROLLED TRIAL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/12/007547
Enrollment
90
Registered
2016-12-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- PATIENTS UNDERGOING BELOW ELBOW SURGERIES

Interventions

Intervention1: levobupivacaine: local anesthetic, 19 ml 0.375%,only at the time of performing block, perineural administration Control Intervention1: buprenorphine: opioid agonist, 150 microgram,only

Sponsors

Dr Rajendra Prasad Government Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Males and females between the age group 20-60 years, ASA class I-II, BMI 18.5-29.9, Undergoing surgeries of forearm and hand

Exclusion criteria

Exclusion criteria: 1. Patients with ASA grade III, IV and V, 2. Patient refusal for the block, 3. Known hypersensitivity to local anesthetics , 4. Opioid addicts, 5. Systemic diseases ( cardiac, renal or hepatic disease), 6. Uncooperative patients, 7. Bleeding disorders, 8. Anatomical abnormality/ infection at the regional site , 9. Patients with partial blocks

Design outcomes

Primary

MeasureTime frame
evaluate and compare the onset, duration of sensory and motor blockade with addition of buprenorphine and butorphanol to levobupivacaineTimepoint: evaluate and compare the onset in 5,10,15,30 mins, duration of sensory and motor blockade with addition of buprenorphine and butorphanol to levobupivacaine in 24 hrs—

Secondary

MeasureTime frame
Hemodynamic stability of buprenorphine and butorphanol in axillary blockTimepoint: 5 minutes, 10 minutes, 15 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, and 120 minutes—

Countries

India

Contacts

Public ContactShelly Rana

Dr. R.P.G.M.C KANGRA

ranipoonamverma@gmail.com9805017320

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026