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Effect of skull bone flap removal on adequacy of brain blood flow in severe head injury

Effect of Decompressive Craniectomy on Jugular Venous Oximetry In Patients With Severe Traumatic Brain Injury - De-JOx

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2016/12/007539
Enrollment
30
Registered
2016-12-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- SEVERE HEAD INJURY WITH GLASGOW COMA SCALE LESS THAN 9 AFTER RESUSCITATION AND HAVING INDICATION OF DECOMPRESSIVE CRANIECTOMY

Interventions

Intervention1: Decompressive craniotomy: Decompressive craniotomy will be done in patient with severe traumatic brain injury if intracranial pressure is persistently high i.e. more than 25 mm Hg for m

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 18-65 yrs 2.Glasgow coma scale score 3.Having indication for decompressive craniectomy: -Sustained ICP elevation >25 mm Hg for more than 30 min in an hour.

Exclusion criteria

Exclusion criteria: 1. ASA physical status IV/ V 2. Brain mass lesion 3. Patient with past history of any intracranial surgery 4. Patient with coagulation abnormality 5. Unstable cervical spine injury

Design outcomes

Primary

MeasureTime frame
To compare values of SjVO2 pre and post decompressive craniectomy.Timepoint: after insertion of jugular venous catheter (preoperative)to 12 hours postoperative period—

Secondary

MeasureTime frame
1. To correlate minimum values of SjVO2 with the outcome. 2. To correlate changes in values of SjVO2 with the outcome. 3. To correlate values of SjvO2 and ICP before and after DC. 4. To correlate changes in values of AVDO2, AVDG and VADL with the outcome.Timepoint: after insertion of jugular venous catheter to discharge from the hospital.—

Countries

India

Contacts

Public ContactDr Navdeep Sokhal

AIIMS, New Delhi

drnavdeep_kumar@yahoo.com01126593474

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026