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Feasibility and safety of Umbilical cord blood as a potential source for blood transfusion in neonates.

Feasibility and safety of Umbilical cord blood as a potential source for blood transfusion in neonates - Prospective cohort study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2016/12/007536
Enrollment
200
Registered
2016-12-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- umbilical cord blood collection and storage

Interventions

Intervention1: umbilical cord blood collection and storage.: Following delivery of baby and delayed cord clamping (1-3 minutes), Umbilical cord blood collected from umbilical vein via gravity into a c
Free Haemoglobin at 0, 14, 28 days
cord blood cultured at 0,14 days . The yield of RBCs estimated after centrifugation of stored blood at 2250 rpm for 12 min at 22 degree Celsius.

Sponsors

Institute of Child Health and hospital for ChildrenDepartment of Neonatology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Mothers who consent for collection and storage of their Umbilical cord blood at the time of delivery

Exclusion criteria

Exclusion criteria: 1. Mothers diagnosed with HIV/HBV/HCV/Malaria/Syphilis infection 2. Mothers who opt for stem cell storage from Umbilical cord blood.

Design outcomes

Primary

MeasureTime frame
1. Quantity of umbilical cord blood (ml) that can be collected per neonate across different gestational age, birth weight, mode of delivery and collection method 2. Change in Parameters of collected and stored umbilical cord blood â?¢ pH (0, 7, 14, 21, 30 days) â?¢ Potassium (0, 7,14,21,30 days) â?¢ Haematocrit (0, 7,14,21,30 days) â?¢ Free Haemoglobin (0, 14, 28days) â?¢ Cord blood culture (0,14 days) Timepoint: 0, 7, 14, 21, 30 days

Secondary

MeasureTime frame
Quantity of packed RBC(ml) that can be separated from the umbilical cord blood after collection.Timepoint: day 1

Countries

India

Contacts

Public ContactDrMangala BharathiS

Madras Medical college

drmangalabharathi@gmail.com09840786836

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026