Comparison of effects of two local anesthetic drugs levobupivacaine and bupivacaine combined with an opioid named fentanyl in spinal anesthesia in patients of Medical Termination of Pregnancy with sterilization surgery

A comparative study of intrathecal low dose hyperbaric levobupivacaine (0.5%) plus fentanyl and low dose hyperbaric bupivacaine (0.5%) plus fentanyl in patients undergoing Medical Termination of Pregnancy with sterilization

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/12/007516

Enrollment

Registered

2016-12-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Pregnant females upto 12 weeks posted for Medical Termination of Pregnancy and sterilisation surgery

Interventions

Intervention1: Fentanyl: Opioid analgesic added in both grouos Control Intervention1: Levobupivacaine: Local anesthetic agent. Levo rotatory isomer of bupivacaine Control Intervention2: Bupivacaine: L

Eligibility

Inclusion criteria

Inclusion criteria: Weight 40-70 kg, Height >145 cm,ASA I-II, Patients under Medical Termination of Pregnancy with sterilisation

Exclusion criteria

Exclusion criteria: Patients with uncontrolled hypertension ,Infection at injection site, Coagulation disorder, Neurological disease, Patient refusal

Design outcomes

Primary

Measure	Time frame
Duration of sensory blockTimepoint: Time to complete recovery of sensory block assessed by pin prick	—

Secondary

Measure	Time frame
Duration of motor block Timepoint: Time to reach Modified Bromage Score to zero.	—

Countries

India

Contacts

Public ContactDr Rama Chatterji

S.M.S. Medical College and Hospital ,Jaipur

drsakshiarora88@gmail.com9571241824

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026