The Effect of Vitamin B12 And/Or Folic Acid Supplementation in Early Childhood on Neurodevelopment; 6- 7 Years Later

Conditions

None listed

Rukman Manapurath, Tor A. Strand, Ranadip Chowdhury, Ingrid Kvestad, Chittaranjan S. Yajnik et al. (7 authors)

Journal of Nutrition2023-03-066 citations

10.1016/j.tjnut.2023.03.003

Vitamin D status in early childhood is not associated with cognitive development and linear growth at 6–9 years of age in North Indian children: a cohort study

Ranadip Chowdhury, Sunita Taneja, Ingrid Kvestad, Mari Hysing, Nita Bhandari et al. (6 authors)

Nutrition Journal2020-02-1030 citations

10.1186/s12937-020-00530-2

Does early vitamin B<sub>12</sub> supplementation improve neurodevelopment and cognitive function in childhood and into school age: a study protocol for extended follow-ups from randomised controlled trials in India and Tanzania

Brita Askeland Winje, Ingrid Kvestad, Krishnamachari Srinivasan, Karim Manji, Sunita Taneja et al. (18 authors)

BMJ Open2018-02-0138 citations

10.1136/bmjopen-2017-018962

Interventions

Control Intervention1: Not Applicable: Not Applicable

Eligibility

Inclusion criteria

Inclusion criteria: Children who participated in the trial in 2010-2011 and who consent to participate in the follow-up study

Exclusion criteria

Exclusion criteria: Non Consent

Design outcomes

Primary

Measure	Time frame
-Weight height, skin fold thickness Neurodevelopment and cognitive functioning through -Wechsler Intelligence Scale -Neuropsychological battery test -Behavior Rating Inventory of Executive Function -Strengths and Difficulties Questionnaire - Childrenâ??s Sleep Habits Questionnaire - Micronutrient status:Hb, folate, cobalamin, holotranscobalamin, MMA, ferritin, vitD, transferrin receptor - Markers of metabolic diseases CRP, Leptin,adiponectin, HbA1c,VCAM-1,ICAM-1,GhrelinTimepoint: -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation)	—

Measure

Time frame

-Weight height, skin fold thickness Neurodevelopment and cognitive functioning through -Wechsler Intelligence Scale -Neuropsychological battery test -Behavior Rating Inventory of Executive Function -Strengths and Difficulties Questionnaire - Childrenâ??s Sleep Habits Questionnaire - Micronutrient status:Hb, folate, cobalamin, holotranscobalamin, MMA, ferritin, vitD, transferrin receptor - Markers of metabolic diseases CRP, Leptin,adiponectin, HbA1c,VCAM-1,ICAM-1,GhrelinTimepoint: -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation) -At enrolment (5 to 6 years after supplementation)

—

Secondary

Measure	Time frame
-Timepoint: -	—

Countries

India

Contacts

Public ContactDr Sunita Taneja

Centre for Health Research and Development, Society for Applied Studies

sunita.taneja@sas.org.in011-46043751-55

Outcome results