A clinical trial to study the effects of intravenous dexmedetomidine on patients comfort , sedation, haemodynamic stability during awake fiberoptic intubation in cervical mylopathy patients.

Efficacy of dexmedetomidine on patients comfort,sedation,haemodynamic stability during awake fiberoptic intubation in cervical spondylotic mylopathy for elective surgery.

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2016/10/007410

Enrollment

Registered

2016-10-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Cervical spodylotic myelopathy patients not responding to medical management ,American Society of Anaesthesiologists-Physical Status I & II

Interventions

Intervention1: study group-- 1)intravenous dexmedetomidine before awake fiberoptic intubation- 1 ug/kg for first 10 min and followed by 0.5 ug/kg/hr . : This study was conducted on 56 adult CSM patie

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either sex aged 18-60 yr, ASA grade I, II posted for cervical spine fixation(elective) surgery under general anaesthesia (GA)

Exclusion criteria

Exclusion criteria: a. Unwilling and uncooperative patient. b. Patient with severe respiratory, cardiovascular, renal diseases. c. Haemodynamically unstable patient. d. ASA grade III and IV. e. Patients on medication like ACE inhibitor, alpha- antagonist and long term use of benzodiazepine and tricyclic antidepressant. f. Comatose patient. g. Patient requiring emergency cervical spine surgery. h. Any type of A-V block, severe bradycardia.

Design outcomes

Primary

Measure	Time frame
I. assessment of patientâ??s sedation and alertness by using Observerâ??s Assessment of Alertness/Sedation Scale (OAA/S scale) 2.comfort during the procedure by postoperative VISUAL ANALOG SCALE(VAS). Timepoint: During awake fiberoptic intubation	—

Secondary

Measure	Time frame
haemodynamic changes-- change of pulse rate, mean blood pressure and respiratory rate.Timepoint: before starting awake fiber optic intubation to five minutes after intubation.	—

Countries

India

Contacts

Public ContactDR Saikat Niyogi

Bangur institute of neurosciences

saikatneuro1972@gmail.com9831732443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026