A clinical trial to study the effect of a drug, dexamethasone on pain relief in children after kidney surgery under general anaesthesia.

Effect of a single dose of dexamethasone on postoperative pain relief in children undergoing elective kidney surgery under general anaesthesia.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/10/007408

Enrollment

Registered

2016-10-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- children aged 2-8 years with kidney disease like wilms tumour,nephroblastoma ,pelviureteric junction obstruction

Interventions

Intervention1: normal saline: normal saline was a comparator agent ( against dexamethasone) to study the efficacy of post operative pain relief in children undergoing elective kidney surgery. Interven

Eligibility

Inclusion criteria

Inclusion criteria: children aged 2-8 years with kidney disease like wilms tumour,nephroblastoma ,pelviureteric junction obstruction

Exclusion criteria

Exclusion criteria: allergy or hypersensitivity to dexamethasone, emergency procedure, prematurity, children with developmental delay, mental retardation or upper respiratory tract infection, history of oral or inhaled steroid intake in previous 6 months, diabetes mellitus

Design outcomes

Primary

Measure	Time frame
to assess the time to first rescue analgesia after single preoperative dose of dexamethasone.The observations were made at- immediate postoperatively, 1 hour, 2 hour,3 hour, 4 hour,8 hour,12 hour and 24 hourTimepoint: Immediate postoperatively, 1hour,2 hour,3 hour,4 hour,8 hour,12 hour and 24 hour	—

Secondary

Measure	Time frame
To assess the effect of single preoperative dexamethasone on - â?¢ Postoperative dose and number of rescue analgesic required in 24 hours. â?¢ Postoperative pain intensity using CHEOPS score. â?¢ Postoperative vomiting:number of episodes and amount of antiemetic required in 24 hours. Timepoint: every hour for 4 h and at 8 h, 12 h and 24 h.	—

Countries

India

Contacts

Public Contactnitin rai

PGIMER CHANDIGARH

neerja.bhardwaj@gmail.com9815174439

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026