Effects of intraoperative liberal fluid therapy on postoperative nausea and vomiting in children

effects of intraoperative liberal fluid therapy with crystalloids on postoperative nausea and vomiting in children undergoing elective lower abdominal and penile surgeries

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/10/007371

Enrollment

150

Registered

2016-10-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O746- Other complications of spinal andepidural anesthesia during labor and delivery

Interventions

Intervention1: liberal intraoperative fluid therapy: 30 ml/kg/hour of Ringer Lactate solution Control Intervention1: restrictive intraoperative fluid therapy: 10 ml/kg/hour of Ringer Lactate solution

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II children of the above mentioned age group of either sex undergoing elective lower abdominal and penile surgeries of duration 30 to 60 minutes

Exclusion criteria

Exclusion criteria: 1. antiemetic therapy within 24 hours before surgery. 2. cardiovascular and renal disease. 3. H/O motion sickness and/or PONV in patient, siblings and parents. 4. obesity - BMI > 30 kg/m2 5. children whose parents cannot be contacted by telephone. 6. contraindication to caudal block. 7 H/O allergic reaction to drugs used in the study

Design outcomes

Primary

Measure	Time frame
complete response (no nausea or vomiting with no administration of any antiemetic medication during 24 hours)Timepoint: 0-6 hours, 6-24 hours and 0-24 hours	—

Secondary

Measure	Time frame
1. pain ( FLACC score greater than 4) 2. fever 3. increased thirst 4. overall parent satisfaction scoreTimepoint: 0-6 hours, 6-24 hours and 0-24 hours	—

Countries

India

Contacts

Public ContactVighnesh Ashok

PGIMER

ibalapgi@gmail.com08557826979

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026