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effect of dexamethasone in reducing pain after gall bladder operation

A study on effect of single dose administration of dexamethasone on postoperative pain in patients undergoing laparoscopic cholecystectomy - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2016/10/007362
Enrollment
100
Registered
2016-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of laparoscopic cholecystectomy between age 18 and 65 years with no comorbidities

Interventions

Intervention1: Dexamethasone: single dose of 8 mg intravenous to be administered during induction of anaesthesia Control Intervention1: NOT APPLICABLE: NOT APPLICABLE

Sponsors

Dr Surendra Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and ASA 2 patients posted for laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: a) Use of steroids within one month of surgery b) Chronic pain requiring opioid treatment c) History of allergy to any study medications d) Patients with renal disease (serum creatinine more than 1.6 mg/dl) e) Patients with liver disease (liver enzymes more than two times of normal values) f) Pregnancy or menstruation g) Diabetes mellitus h) Co-existing GI pathology (e.g. gastric ulcer, ulcerative colitis, Crohnâ??s disease etc.) i) Psychiatric disorder j) History of alcohol or drug abuse k) Conversion from laparoscopic cholecystectomy to open procedure l) Patients who are immunosuppressed or undergoing immunosuppression therapy

Design outcomes

Primary

MeasureTime frame
less postoperative painTimepoint: 48 hours

Secondary

MeasureTime frame
reduced postoperative nausea and vomitingTimepoint: 24 hrs

Countries

India

Contacts

Public ContactDr Surendra Singh

Sanjay Gandhi Postgraduate Institute of Medical Sciences

sourangshu.sarkar@gmail.com8004904604

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026