Health Condition 1: null- Children already selected for flexible bronchoscopy due to a medical indication as already decided by the professor of the division of paediatric puomonology of the institution.
Conditions
Interventions
Intervention1: Nebulization of lignocaine (Nebulization arm): Children who are randomly allocated to this intervention arm will be nebulize with 4mg/kg lignocaine using a jet nebulizer 15min prior to
Sponsors
All India Institute of Medical SciencesDelhi
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 1 month to 16y who are already selected for flexible bronchoscopy under conscious sedation due to a medical indication as decided by the in-charge professor of the unit to do at the paediatric bronchoscopy suite, AIIMS-Delhi.
Exclusion criteria
Exclusion criteria: 1. History of any kind of adverse reaction to lignocaine given by any route 2. History of any adverse reaction to any other medication which use in the procedure (Atropine, Midazolam, Fentanyl) 3. Children who are already given sedative drugs or lignocaine within 72hours of the procedure. 4. Children who are already on ventilatory support via ETT or tracheostomy 5. Children with SpO2 6. Children with GCS 7. Already diagnosed children with cardiac arrhythmias 8. Already diagnosed children with acute or chronic, liver or renal failure 9. Not consented
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of the childâ??s cough during the procedure (Number of cough episodes per a minute)Timepoint: Count the number of time child cough during the procedure by watching a video record of the procedure. It will be divided by total time of the procedure to get rate. This will be done by two blinded observers who are not directly participate for the study in separate sessions of 10 participants videos at a time. | — |
Secondary
| Measure | Time frame |
|---|---|
| Bronchoscopistâ??s and bronchoscopy nurseâ??s overall feeling about the easiness of the procedureTimepoint: Physician who did the bronchoscope and nursing sister who assisted for the procedure will give an overall rate about the easiness of the procedure using a 100mm VAS within 15min after completion of bronchoscopy.;Desaturations during the procedure (SaO2 drop more than 5 percent from Baseline)Timepoint: Document SaO2 before nebulization and continuous monitoring of SaO2 during and up to 1 hour after procedure with a pulse oxymeter. Total duration of desaturation more than 5 percent from baseline is measured in seconds using a stop watch;Haemodynamic stability Maximum fluctuation of pulse rate.Timepoint: Difference between maximum and minimum pulse rate (Expressed as percentage deviation from baseline value);Haemodynamic stability Maximum rise in pulse rate.Timepoint: Maximum pulse rate during and 1h following the procedure will be noted while, continuously monitoring pulse rate with a pulseoxymeter. (Expressed as percentage deviation from baseline value);Haemodynamic stability-Maximum drop in pulse rateTimepoint: Minimum pulse rate during and 1h following the procedure will be noted while, continuously monitoring pulse rate with a pulseoxymeter. (Expressed as percentage deviation from baseline value);Intensity of stridor which developed or worsened due to the procedureTimepoint: Same observers who count the frequency of cough will also give a rating regarding the intensity of the stridor using a 100mm Visual Analogue Scale after watching the video recording.;Intensity of the cough of the participant during the procedureTimepoint: The blinded observers who count the frequency of cough will give a rating regarding the intensity of the cough using a 100mm VAS after watching the video recording.;Minimum O2 saturation detected during the procedure and the percentage drop from baseline.Timepoint: Minimum SaO2 during and 1h following the procedure is documented and per | — |
Countries
India
Contacts
Public ContactSETHUGE SAJITH CHANNA DE SILVA
All India Institute of Medical Sciences-Delhi
Outcome results
None listed