Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 2: null- patients with acute pancreatitis diagnosed as per revised Atlanta classification within 7 days of onset of illness
Conditions
Interventions
Intervention1: Diclofenac Sodium (NSAID): It is to be given 75 mg intravenous route every 8 hourly till 40 hours.
Control Intervention1: Pentazocine (opoid analgesic): It is to be given 30 mg intraven
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: patients with acute pancreatitis diagnosed as per revised Atlanta classification will be included.Patients should have abdominal pain at enrollment and should be hospitalised within 7 days of onset of acute pancreatitis
Exclusion criteria
Exclusion criteria: 1. Patients with organ failure (as defined by revised Atlanta classification) at enrollment 2. Patients with altered sensorium 3. Patients with a serum creatinine > 1.5 mg/dl 4. Patient with a known coronary artery disease 5. Patients admitted after 7 days of onset of acute pancreatitis 6. Patients with paralytic ileus as defined by abdominal distention, absent bowel sounds and dilated loops on intestine 7. Patients with evidence of chronic pancreatitis 8. Refusal to give consent 9. Age 75 year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Difference in efficacy of interventional analgesics for pain relief in terms of total dose and number of bad demands of rescue analgesia 2. The need for crossover of intervention analgesicTimepoint: From enrollment till 40 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in adverse events between the groupsTimepoint: from enrollment till 5 days | — |
Countries
India
Contacts
Public ContactSoumya Jagannath Mahapatra
All India Institute of Medical Sciences
Outcome results
None listed