Health Condition 1: null- Children aged 1 month to 12 years of adult parents with coma due to acute CNS infections
Conditions
Interventions
None listed
Sponsors
JIPMER intramural grant
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 1 month to 12 years of adult parents with coma due to acute CNS infections
Exclusion criteria
Exclusion criteria: 1. Patients with metabolic coma like diabetes mellitus / diabetic ketoacidosis (DKA), liver failure, hypertensive encephalopathy and Reyeâ??s syndrome. 2. Patients with suspected / proven inborn error of metabolism (IEM). 3. Known case of developmental delay. 4. Brain death at the time of admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the association between glucose variability (hyperglycemia, hypoglycemia and fluctuation) and the proportion of patients who developed new onset organ dysfunction (based on PELOD score during PICU stayTimepoint: at 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the association between glucose variability and composite poor outcome at 90-days (mortality or severe neurodisability).Timepoint: At 3 months;To study the association between glucose variability and length of mechanical ventilation if ventilated and hospital stay including PICU stay.Timepoint: At hospital discharge.;To study the association between glucose variability and proportion of patients requiring organ support intervention (inotropic support, renal replacement therapy).Timepoint: at PICU discharge | — |
Countries
India
Contacts
Public ContactDr Ramesh Kumar R
JIPMER
Outcome results
None listed