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Comparison of Turmeric versus Chlorhexidine in the treatment of gum diseases.

Evaluation of Turmeric chip compared to Cholrhexidine chip as a local drug delivery agent in the treatment of Chronic Periodontitis Patients- A split mouth Randomised Controlled Clinical Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/09/007280
Enrollment
40
Registered
2016-09-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic Mild to moderate Periodontitis

Interventions

Intervention1: Turmeric chip : Turmeric Chip: Turmeric chip was prepared in the lab in Guru Nanak Institute of Pharmacy, Ibrahimpatnam, Hyderabad. The size of the chip is 4 x 5mm with a thickness of

Sponsors

Dr Abhilasha Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with chronic periodontitis having at least 3 periodontal sites with pocket depth 5mm to 8mm. 2. Patients without any history of drug allergy to chlorhexidine. 3. Patients not using any medicated toothpaste/ antibacterial mouthwash/ antibiotics or any anti-inflammatory drug before the commencement of the study for at least the past 3 months.

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating females. 2. Patients with a history of any kind of periodontal therapy within past 6 months. 3. Medically compromised patients and patients having debilitating diseases.

Design outcomes

Primary

MeasureTime frame
Both the drugs were equally effective not only in reducing plaque and gingival inflammation but also in reducing pocket depths and causing significant gain in attachment level as evident by the statistically significant reduction in all the parameters including PI, GI,PPD and RAL (probability value less than 0.001) and both the drugs were significantly more efficient than Scaling and root planing alone (SRP) alone as a therapy.Timepoint: baseline 1 month 3months

Secondary

MeasureTime frame
Both the drugs were equally acceptable without any adverse drug reactions mentioned in previous studies regarding Chlorhexidine.Timepoint: baseline, 7 days.

Countries

India

Contacts

Public ContactAbhilasha Singh

Modern Dental College and Research Centre

drrajasridhar@rediffmail.com9329729790

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026