Health Condition 1: null- patients (new born babies) who were asphyxiated at birth means not cried at birth
Conditions
Interventions
Intervention1: cooling material: techotherm and phasechanging material
Intervention2: therapeutic hypothermia: techotherrm phase changing material
Intervention3: therapeutic hypothermia: whole body hy
Sponsors
Dr Vishnubhat
Eligibility
Inclusion criteria
Inclusion criteria: a. Inclusion Criteria (1,2,3 + Any one of 4 ) 1. Gestational, age >= 37 weeks 2. ABG(umbilical cord or 1st postnatal hour pH = 12meq 3. Evidence of encephalopathy (Sarnat staging) 4. Any one of the following i. APGAR ii. Assisted ventilation for at least 10 min after birth iii. Evidence of any organ dysfunction iv. History of acute perinatal event- intra partum fetal distress, cord prolapse placental abruption.
Exclusion criteria
Exclusion criteria: 1. Infants >6 hours of age at the time of randomization 2. Major congenital abnormalities 3. No spontaneous respiration by 20 minutes 4. Extramural babies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To study the effect of hypothermia on myocardial ejection fraction and myocardial enzyme profile in term newborns with perinatal asphyxiaTimepoint: 0&72 hrs ECHO for ejection fraction 0&24&72 hrs for enzyme profile | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To correlate the change in myocardial ejection fraction and myocardial enzyme profile with severity of asphyxia and neuro developmental outcome at 18 months.Timepoint: 18 months | — |
Countries
India
Contacts
Public ContactVishnu Bhat
jipmer
Outcome results
None listed