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Use of corticosteroids for Third Molar Surgery

Randomized Placebo Control Open label trial for evaluation and comparison of effect of Submucosal Injection of Dexamethasone and Methylprednisolone on Postoperative Discomfort after Third Molar Surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/09/007255
Enrollment
60
Registered
2016-09-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Third Molar surgery

Interventions

Intervention1: Dexamethasone 8 mg submucosally: 8 mg dexamethasone will be infiltrated submucosally around the site of surgery at approximately 5â??10 min. preoperatively. Control Intervention1: Methy

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of age group 18-40 years 2. Pell and Gregory Class II with position A would be minimum selection criteria. 3. Third molar involved should be free of caries, extensive periodontal disease, pain, or other inflammatory symptoms at the time of operation

Exclusion criteria

Exclusion criteria: 1. Patients with immunocompromised status, uncontrolled systemic disease, presence of infection, pregnancy or lactation. 2. Absolute contraindications to corticosteroid use like patients with tuberculosis, active viral or fungal infections, active acne vulgaris, and primary glaucoma, a history of acute psychosis or psychopathic tendencies and allergies.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of 40 mg submucosal methylprednisolone and 8 mg submucosal dexamethasone in reducing pain, swelling and trismus in contrast to no steroids in control patients following surgical removal of impacted mandibular third molars.Timepoint: Data evaluation of patients - 10 months Next 2months Statistical Evaluation and Final Result

Secondary

MeasureTime frame
NoneTimepoint: None

Countries

India

Contacts

Public ContactDr Ankita Chugh

AIIMS Jodhpur

ankitamody@gmail.com8003996891

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026