Health Condition 1: null- Patients with cholecystitis undergoing laparoscopic holecystectomy and experiencing hemodynamic surges during laparoscopy
Conditions
Interventions
Intervention1: Magnesium Sulphate: Injection magnesium sulphate I.P. 50% (w/v)added to 100 mL of normal saline and given as infusion over 10 minutes, before induction of anesthesia
Control Interventio
Sponsors
Jaipur Golden Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA physical staus I and II patients 2. Aged 20-60 years 3. Both sexes 4. Presenting for elective laparoscopic cholecystectomy under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients who do not give informed consent. 2. ASA III and above patients. 3. Patients with history of neuromuscular disease, drug or alcohol abuse, coronary artery disease (CAD), cardiac arrhythmia, hypermagnesemia, neuromuscular disease, increased intraocular pressure, hiatal hernia, or gastroesophageal reflux. 4. Patients with anticipated difficult airway. 5. Patients taking calcium channel blockers. 6. Patients having known sensitivity to the study drug. 7. Pregnant women and lactating mothers 8. Patients in whom surgery could not be completed laparoscopically.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Attenuation of hemodynamic surges during intubation and those due to pneumoperitoneumTimepoint: immediately after intubation, 3 minutes after intubation, then throughout pneumoperitoneum | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduced incidence of post-operative nause, vomiting and shiveringTimepoint: Immediate post-operative period to 120 minutes post-operatively | — |
Countries
India
Contacts
Public ContactDr Ramesh Subedi
Jaipur Golden Hospital
Outcome results
None listed