Skip to content

A study looking at the likelihood of bleeding and platelet requirements in blood cancers.

Prospective observational study to determine bleeding risk and platelet transfusion requirements in haematological malignancies.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2016/08/007227
Enrollment
100
Registered
2016-08-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Cancer patients with hematological malignancies.

Interventions

None listed

Sponsors

Tata Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between age 1 and 60 years presenting to TMH, Parel with de novo hematological malignancy (newly diagnosed and not having received chemotherapy outside) and who will be treated with curative intent.

Exclusion criteria

Exclusion criteria: 1) Those will myelodysplastric syndromes. 2) Those with secondary leukemias. 3) Those who have received prior chemotherapy.

Design outcomes

Primary

MeasureTime frame
The study is intended to arrive at a bleeding risk index for Indian patients with hematological malignancies undergoing chemotherapy.Timepoint: First itme point will be when the patient is enrolled into study. Second time point is after completion of first phase of chemotherapy. Third time point will be after completion of second phase of chemotherapy.

Secondary

MeasureTime frame
1) Revisit the prophylactic thresholds for various co morbidities, namely: febrile neutropenia, fungal pneumonia, oral mucositis in adults and sepsis. 2) % of outpatients with stable thrombocytopenia and platelet count above 20k/µl, who were given platelets. 3)% of inpatients with stable thrombocytopenia and platelet count above 10k/µl, who were given platelets. 4) To correlate the grade of bleeding (WHO grades) and the platelet counts at which they occurred. Timepoint: 1) During first phase of chemotherapy 2) During 2nd phase of chemotherapy

Countries

India

Contacts

Public ContactDr Parayacade Joseph Sanal

Tata Memorial Hospital

sunilrajadhyaksha@gmail.com02224127096

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026