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Prolonged postoperative surgical pain after laparoscopic cholecystectomy

Incidence of chronic postoperative surgical pain after laparoscopic cholecystectomy:A comparison between dexmedetomidine- fentanyl and propofol-fentanyl based total intravenous anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/08/007200
Enrollment
100
Registered
2016-08-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Inclusion criteria: Scheduled for elective laparoscopic cholecystectomy Patients aged 18-60 years American Society of Anesthesiologists Physical Status I & II

Interventions

Intervention1: Propofol-fentanyl group: Induction with injection propofol 1.5mg/kg IV and maintenance with 3-12mg/kg/h propofol infusion along with fentanyl infusion at rate of 1mcg/kg/hr. Control In

Sponsors

DirectorSri Venkateswara Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: Scheduled for elective laparoscopic cholecystectomy Ppatients aged 18-60 years American Society of Anesthesiologists Physical Status I & II15

Exclusion criteria

Exclusion criteria: Exclusion criteria: Chronic opioid users Pre-existing pain syndrome Severe cardiovascular(New York Heart Association class III or IV) Severe pulmonary and renal disease Inability to communicate and understand Pain scale(Visual analogue scale) Pregnant and lactating mothers Patients not willing to participate in the study.

Design outcomes

Primary

MeasureTime frame
1. Primary objective is to find out the incidence of chronic post-operative surgical pain(CPSP) after laparoscopic cholecystectomyTimepoint: At 1st,2nd,3rd and 4th months after surgery

Secondary

MeasureTime frame
2. Secondary objective is to compare the (1)incidence of CPSP and (2)recovery profile between two different types of TIVA.Timepoint: (1)1st ,2nd ,3 rd and 4th month after laparoscopic cholecystectomy (2)Post operative period (time frame 0-24h)

Countries

India

Contacts

Public ContactDr Aloka Samantaray

Department of Anaesthesiology& Critical Care Sri Venkateswara Institute of Medical Sciences Tirupati

himabindukotamarthy@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026