Health Condition 1: null- To study the early post operative outcomes in patients who undergoe live donor liver transplantation as per standard accepted criteria.Outcome in donors who undergoe the donor surgery is also studied
Conditions
Interventions
Intervention1: Extended Graft Group[Native middle hepatic vein]: Patients are randomized to groups were either the middle hepatic vein is taken from the donor or not.
Intervention2: NIL: NIL
Control I
Sponsors
Christi Titus Varghese
Eligibility
Inclusion criteria
Inclusion criteria: .Patients with liver disease who meet the criteria for live donor liver transplantation .Live donor suitable for extended right hepatectomy[with middle hepatic vein] a.Has a future liver remnant of more than 30% b.Live donor with adequate segment 4a drainage to left hepatic vein[usually a umblical vein] c.Steatosis less than 20% as assessed by L-S ratio on plain CT.
Exclusion criteria
Exclusion criteria: .Thrombosed recipient portal Vein. .Graft to recipient wight ratio less than 0.7. .Venous drainage of segment 4 mainly to middle hepatic vein in donor .ABO incompatible liver transplants .Donor at or above 55 years of age
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Change in post surgery liver parameters in donor and recipientTimepoint: Untill discharge/ 1Month [whichever comes later] | — |
Primary
| Measure | Time frame |
|---|---|
| Recipient: Early Allograft Dysfuction[EAD] Small for size Syndrome[SFSS] Primary graft non function[PGNF} Patency of Middle hepatic vein Number of days in ICU Mortality at the end of 90 days Donor: Post Hepatectomy liver failure[PHLF} Post operative Clavien-Dindo score Number of days in hospital after surgery CT based volume regeneration at the end of 60 daysTimepoint: All parameters uptil discharge/one month[which ever comes later] or as specified with the outcome. | — |
Countries
India
Contacts
Public ContactChristi Titus Varghese
Amrita Institute Of Medical Sciences
Outcome results
None listed