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IS THYROXINE TREATMENT REQUIRED IN PREGNANT HYPOTHYROID WOMEN WHO IS ANTIBODY NEGATIVE

A PROSPECTIVE RANDOMIZED CONTROL TRIAL COMPARING CLINICAL OUTCOME OF THYROXINE SUPPLEMENTATION IN THYROID PEROXIDASE ANTIBODY NEGATIVE CASES IN PATIENTS WITH SUBCLINICAL HYPOTHYROIDISM IN PREGNANCY

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/08/007181
Enrollment
60
Registered
2016-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- pregnancy upto 22 weeks

Interventions

Intervention1: tablet levothyroxine: 1.6mcg/Kg body weight per orally ONCE DAILY empty stomach in the morning THROUGHOUT THE PREGNANCY Control Intervention1: tablet glucose: 10 gram per orally ONCE D

Sponsors

ANTENATAL OPD DEPTT OF OBS GYNAE AIIMS PATNAinstitutional
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: all pregnant women with subclinical hypothyroidism and thyroid peroxidase antibody negative

Exclusion criteria

Exclusion criteria: 1. patients with bad obstetric history 2. patients with TSH 4.5 mIU/ml or more at entry point 3. patient having TSH less than 0.1 or more than 4.5 mIU/ml during study

Design outcomes

Primary

MeasureTime frame
pre-term labour, abruption plcentaeTimepoint: pre-term labour, abruption plcentae—

Secondary

MeasureTime frame
aneamia, gestational hypertension, gestational diabetes mellitus, post partum haemorrhage, operative delivery, birth asphyxia, neonatal jaundice, neonatal sepsis, still birthTimepoint: 9 months—

Countries

India

Contacts

Public Contactmukta agarwal
agarwal_mukta2006@yahoo.co.in9661215080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026