Health Condition 1: null- Obese subjects with BMI 25-35 kg/m2 Health Condition 2: E660- Obesity due to excess calories
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a. Adults aged between 20 and 45 years b. Gender Both Male and Female c. BMI - 25-35 kg/m2
Exclusion criteria
Exclusion criteria: a)Subjects enrolled in professional/supervised weight reduction program in last 12 months b)Diabetic patients (Fasting plasma glucose > 126mg/dL) c)Pregnant women d)Subjects with inability or with restrictions to participate in a regular physical activity program e)Subjects with any low grade chronic inflammatory diseases f)Self- reported/previously diagnosed renal, hepatic & thyroid disorder g)Subjects on vitamin D supplementation from last 3 months i.e 1000 IU h)Subjects with heavy alcohol consumption ( >3 drinks/day) and smoking ( >2cigrettes/day)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To quantify the effect of yogaâ??based lifestyle intervention at genetic level by gene expression analysis of TNFα,IL-6, MRPL43, Nuclear factor Erythroid 2 (NFE2) as well as the telomere length and telomerase enzyme activity .Timepoint: 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢Changes in the Vitamin D receptor Gene expression after Yoga based lifestyle intervention â?¢ Quantification of protein level of TNFα, IL-6, MRPL43, Nuclear factor Erythroid 2 (NFE2. Timepoint: 12 weeks | — |
Countries
India
Contacts
AII India Institute of Medical Science,New Delhi-110029