A clinical trial to compare the effects of two methods of obtaining hair stem cells for treating vitiligo

A comparative study to assess the efficacy and composition of various cell populations of extracted hair follicle outer root sheath cell suspensions (EHF ORS CS) prepared using a single enzyme (trypsin) and multiple enzymes (trypsin and collagenase) for transplantation in vitiligo

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/08/007133

Enrollment

Registered

2016-08-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Segmental/generalised, stable vitiligo

Interventions

Intervention1: Dermabrasion followed by application of Cell suspension (EHF ORS CS) prepared using a single enzyme: Extracted hair follicle outer root sheath cell suspension (EHF ORS CS) prepared usin

Eligibility

Inclusion criteria

Inclusion criteria: 1. Segmental or generalised vitiligo 2. Stable for at least 1.5 years 3. One large patch of size at least 18 cm2 OR minimum 3 patches of at least 9cm2 each

Exclusion criteria

Exclusion criteria: 1. Age less than 18 years 2. Pregnancy 3. Koebnerization 4. Keloid or bleeding diathesis 5. Active infection at site 6. Other autoimmune diseases 7. Inability to follow up for at least 6 months 8. Acral sites & bony prominences as recipient sites

Design outcomes

Primary

Measure	Time frame
Percentage repigmentation achieved in the recipient sites of transplantationTimepoint: 6 months post surgery	—

Secondary

Measure	Time frame
Percentage repigmentation achieved in the recipient sites of transplantationTimepoint: 1 week, 1 month, 2 months and 3 months post surgery	—

Countries

India

Contacts

Public ContactDr Somesh Gupta

All India Institute of Medical Sciences (AIIMS)

someshgupta@hotmail.com01126593217

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026