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To compare different fluid therapy approach in renal transplant recipient during transplantation

Comparison of Different Rates of Intraoperative Fluid Therapy on Early Graft Function during Live Related Renal Transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/07/007111
Enrollment
40
Registered
2016-07-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- chronic kidney disease stage 5

Interventions

Intervention1: Targeted therapy group: Patients will receive intra venous fluid at rate of 1ml/kg/hr from start of surgery till start of vascular anastomosis. Any blood loss occurring below the allowa

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing live related renal transplantation. Donor graft is procured by laparoscopic nephrectomy

Exclusion criteria

Exclusion criteria: Severe left ventricular dysfunction Cardiomyopathy with ejection fraction less than 40%. Diabetics Post dialysis hemoglobin less than 8 gm % Severe pulmonary disease and liver disease Refusal to participate in the study Vascular anomaly of donated organ Intraoperative transfusion of blood

Design outcomes

Primary

MeasureTime frame
Serum creatinine level on postoperative day 1 in patients receiving fluid according to two different fluid regimensTimepoint: Serum creatinine level on postoperative day 1 in patients receiving fluid according to two different fluid regimens

Secondary

MeasureTime frame
24 hour urine outputTimepoint: post op day 1;4 hour urine output after declamping of vesselsTimepoint: 4 hours following declamping;Any signs of fluid overloadTimepoint: till post of day 6;Fall in serum creatinine ,blood urea and serum electrolytes as compared to Preoperative levelTimepoint: patient followed till post op day 6;Need for postoperative hemodialysisTimepoint: till post op day 6;Onset of urine production in graft after declamping of vesselsTimepoint: immediately after declamping of renal artery

Countries

India

Contacts

Public ContactAbhishek singh

ALL INDIA INSTITUTE OF MEDICAL SCIENCES

rashmiramachandran1@gmail.com9868397812

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 13, 2026