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Prospective study to assess the efficacy and safety of different doses of antihistamines in treating chronic spontaneous urticaria

Prospective open label study to assess the efficacy and safety of step-wise increase in dose of antihistamines in treating chronic spontaneous urticaria

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2016/07/007099
Enrollment
96
Registered
2016-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic spontaneous urticaria

Interventions

Intervention1: Levocetrizine: All patients will be treated with levocetirizine 5mg per day. Those patients whose symptoms are not completely controlled with 5mg levocetirizine, will be treated with we

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients >18 years of age 2.Patients fulfilling the definition of chronic spontaneous urticaria which is urticarial lesions occurring most days of the week (atleast 3 times a week) lasting for 6 weeks or more with no identifiable cause on history or examination.

Exclusion criteria

Exclusion criteria: 1. Patients less than 18 years of age, 2. Patients unwilling to participate in the study, 3. Patients with physical, contact, drug-induced urticaria and urticarial vasculitis 4. Pregnant or breast-feeding females

Design outcomes

Primary

MeasureTime frame
Proportion of patients achieving complete control of urticaria with varying doses of antihistaminesTimepoint: From September 2014 to September 2015

Secondary

MeasureTime frame
â?¢Change in Urticaria Activity Score (UAS7) â?¢Change in quality-of-life as measured by CUQ2oL â?¢Degree of sedation experienced as reported by the patients Timepoint: From September 2014 to September 2015

Countries

India

Contacts

Public ContactDr Vinod Kumar Sharma

Dermatology and Venereology, AIIMS

aiimsvks@yahoo.com26593217

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026