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Combined effect of N-acetylcysteine (antioxidant) and 20 minute walk on quality of life in stable COPD (kali Khasi) patients

Study of quality of life in stable C.O.P.D.patients with ten weeks treatment of N-acetylcysteine and home based exercise.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/06/007024
Enrollment
100
Registered
2016-06-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Stable COPD patients

Interventions

Intervention1: N-acetylcystiene and twenty minutes daily walk for ten weeks in addition to standard treatment: Tablet.600 mg N-acetylcytiene(effervecent) o.d. dissolved in water in combined with 20 mi

Sponsors

Dr Vijay Tukaram Salve
Lead Sponsor
Dr Jitesh S Atram
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed as stable COPD on basis of FEV1 according to (GOLD guidelines 2010) of age 40yrs to 70 yrs

Exclusion criteria

Exclusion criteria: Patient in acute exacerbation in last 6weeks, patients with severe ischemic heart disease recent history of MI, stroke, severe hypertension (systolic >180 & diastolic >110),pulse >120, Patients who are unable to walk the predicted distance for their age in six minuteâ??s walk test, pregnant patients,elderly patients above 70 years.If in between the study patient present with acute exacerbation.

Design outcomes

Primary

MeasureTime frame
There was statistically significant improvement in SGRQ-C score and quality of life in the study group P value 0.0001 while improvement in SGRQ-C score and quality of life in control group was not statistically significant.P value 0.118.Overall there was statistically significant improvement in SGRQ-C score and quality of life.P value 0.03 in the study group.Timepoint: Quality of life was assessed with Saint Geoerge Respiratory Questionaire-C(SGRQ-C) at the begining of the study and at the end of ten weeks.

Secondary

MeasureTime frame
Same as primary outcome.Timepoint: There was improvement in the quality of life at the end of ten weeks in study group.

Countries

India

Contacts

Public ContactVijay Tukaram Salve

Indira Gandhi Government Medical College

dr_jitesh0302@rediffmail.com9503109326

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026