Health Condition 1: N429- Disorder of prostate, unspecified Health Condition 2: null- POST TRANS-RECTAL PROSTATE BIOPSY COMPLICATIONS
Conditions
Interventions
Intervention1: Group I: Single dose oral ciprofloxacin prophylaxis(500 mg)given at bed time before procedure.
Control Intervention1: Group II: Three day ciprofloxacin prophylaxis(500mg BD for 3 days)
Sponsors
University College of Medical Sciences University of Delhi Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients aged more than 40 to 80 years in whom transrectal prostate biopsy was indicated and giving informed consent to participate in the study. 2. Patients with indications for transrectal prostate biopsy (PSA >4ng/ml,abnormal/suspicious DRE,symptoms of prostatism, history of prostate carcinoma in first degree relatives)
Exclusion criteria
Exclusion criteria: 1.Patient not willing to give consent for inclusion in the above study. 2.Patient having active untreated genitourinary tract infection (prostatitis, cystitis, Epididymo-orchitis,UTI) 3.Patients with painful, active and untreated anorectal conditions like untreated proctitis, fistula in ano, fissure and hemorrhoids 4. Patients with mental disorders or illness who cannot understand or comply with the study protocol. 5. Patients with known history of allergy to ciprofloxacin therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess positive Urine culture rate in both groups following TR prostate biopsy. 2. To assess pyuria rate in both groups following TR prostate biopsy. 3. To assess hospitalization rates following TR prostate biopsy. 4. To assess positive urine culture rate among two groups.Timepoint: Day 1,2 and 5 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate pain(VAS score) in patients post TR prostate biopsy . 2. To evaluate post TR prostate biopsy hematuria in patients. 3. To evaluate the bacterial spectrum and antimicrobial sensitivity spectrum of rectal flora in patients undergoing TR prostate biopsy 4. To look for any side effect associated with ciprofloxacin therapy in patients post TR prostate biopsy. Timepoint: Day 3 and 5 | — |
Countries
India
Contacts
Public ContactDr Saket Singh
University College of Medical Sciences University of Delhi and GTB Hospital
Outcome results
None listed