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Postoperative pain relief: Comparison of two commonly used agents.

Comparison of the analgesic efficacy of a single dose of epidural dexmedetomidine versus fentanyl as an adjuvant to bupivacaine in abdominal surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/05/006961
Enrollment
60
Registered
2016-05-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Elective abdominal surgical candidates (ASA grade I and II)

Interventions

Intervention1: Dexmedetomidine: Epidural dexmedetomidine 0.5 mcg/kg with 12.5 mg bupivacaine to 10 ml volume in saline postoperatively as single dose Control Intervention1: Bupivacaine: Epidural Cont

Sponsors

Amrita Institute of medical Sciencess and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA I, II patients presenting for elective abdominal surgery.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Patient refusal for epidural procedure 2. ASA III, or higher 3. Emergency surgery 4. Laparoscopic surgery 5. Coagulopathies 6. Patient on clonidine 7. Local infection at the site of epidural insertion

Design outcomes

Primary

MeasureTime frame
Patient Pain ScoreTimepoint: Every 5 min for 15 minute after drug Administration and half hourly therafter—

Secondary

MeasureTime frame
residual motor blockadeTimepoint: Half hourly;Hemodynamic effectsTimepoint: Every 5 minutes for 15 minutes, Half hourly thereafter—

Countries

India

Contacts

Public ContactLakshmi Kumar

Amrita Institute of Medical Sciences and Research Center

lakshmi.k.238@gmail.com04842851234

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026