Health Condition 1: null- Chronic Periodontitis
Conditions
Interventions
Intervention1: Bishosphonate gel: 20 µl of ZLN gel (0.005%) or the placebo gel as measured by micropipette was delivered in the already chosen sites which were the intrabony defects in the experiment
Sponsors
Abhaya Gupta
Eligibility
Inclusion criteria
Inclusion criteria: Systemically healthy chronic periodontitis subjects (30-50 years) having pocket probing depths (PDs) more than or equal to 5mm or clinical attachment levels (CALs) more than or equal to 4mm and vertical bone loss more than or equal to 3 mm on intraoral periapical radiographs or Orthopentomograph were initially included. Only those subjects which on screening by the dentascan showed two walled or combined defects without involving the furcation with radiographic defect angle less than or equal to 45 degrees were selected for the study by an independent blinded investigator.
Exclusion criteria
Exclusion criteria: Individuals allergic to bisphosphonates or on systemic bisphosphonate therapy, tobacco & alcohol users, immunocompromised patients or having taken antibiotics within preceding 3 months, undergone periodontal surgical treatment within last 6 months, pregnant or lactating females were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| full mouth plaque index , gingival index, tooth specific probing depth & clinical attachment levelTimepoint: baseline 3 months 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| defect depth, bucco-lingual width of defect, mesio-distal defect width, radiographic angle fill & volumetric bone gain percentageTimepoint: baseline 6 months | — |
Countries
India
Contacts
Public ContactAbhaya Gupta
Babu Banarasi Das University, lucknow
Outcome results
None listed