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comparison of the effect of two kind of anaesthetic agents on brain physiology in patients undergoing brain tumor removal

comparison of the effect of intravenous and inhalational anaesthetic agents on cerebral hemodynamics assessed by SJVO2 in patients undergoing cerebral tumor resection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/05/006923
Enrollment
45
Registered
2016-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D330- Benign neoplasm of brain, supratentorial Health Condition 2: C710- Malignant neoplasm of cerebrum, except lobes and ventricles Health Condition 3: null- PATIENTS WITH SUPRATENTORIAL SPACE OCCUPING LESION (TUMOUR)

Interventions

Intervention1: Juglar venous oximetry(SJVO2): SJVO2 is basically 5F catheter inserted at juglar bulb via internal juglar vein under all aseptic precaution. This procedure will be done under general an

Sponsors

Postgraduate institute of medical education and research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with supratentorial brain tumor posted for craniotomy and excision

Exclusion criteria

Exclusion criteria: Patient with Glasgow Coma Scale Patient with Midline shift >5mm in CT scan of brain Patient having moderate to severe pulmonary obstruction or restriction Patient having decompensated cardiac disease such as arrhythmias, ischemic or valvular heart disease.

Design outcomes

Primary

MeasureTime frame
compare the effect of intravenous (propofol) and inhalational (sevoflurane and desflurane) anaesthetic agents on cerebral hemodynamics in form of SJVO2 in patients undergoing supratentorial brain tumor resectionTimepoint: October 2015 to September 2016

Secondary

MeasureTime frame
Compare the effect of intravenous (propofol) and inhalational (sevoflurane and desflurane) anaesthetic agents on cerebral haemodynamics in form of arterio-venous oxygen content difference, recovery from anaesthesia in the form of emergence time, tracheal extubation time, recovery time and intraoperative condition of brain in patients undergoing supratentorial brain tumor resectionTimepoint: October 2015 to September 2016

Countries

India

Contacts

Public ContactNARENDER KALORIA

POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH, CHANDIGARH

nidhibp@gmail.com7087009525

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026