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A clinical trial to study the effect of analgesia during labour on post partum depression

Effect of combined spinal-epidural analgesia during labour on post partum depression: a controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/04/006888
Enrollment
130
Registered
2016-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Group 1- Combined Spinal Epidural Group: Parturients belonging to group 1 will receive neuraxial block using combined spinal epidural technique and evaluated for post partum depression

Sponsors

Government Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 and 2 Age more than 18 years Primigravida Single gestation Cephalic presentation at 37 completed weeks of gestation In early spontaneous labour(cervical dilation Baseline pain score >30(on a VAS of 0-100) Able to use PCEA pump Parturients consenting to participate in the study

Exclusion criteria

Exclusion criteria: Refusal by parturient Patient failing to understand the functioning of PCEA pump and VAS scoring History of psychiatric disorder(GHQ12 >2) Obesity(Wt >100kg) Parturients who have received oral or parenteral analgesics in the last 4 hours Systemic and local sepsis Deranged coagulation profile Preterm labour( Obstetric complications(eg., PROM) Foetus with a non re-assuring NST Foetus with known or suspected congenital anomalies Allergy to study drugs i.e., levobupivacaine, fentanyl Patient with Diabetes(pre-existing or gestational) or history of immunosuppression. Patients with hypertension on methyldopa

Design outcomes

Primary

MeasureTime frame
Prevalence(frequency in percentage) of post partum depression using EPDS questionnaireTimepoint: Day 3 and 6 weeks

Secondary

MeasureTime frame
Maternal satisfaction(VAS score) Pain score(VAS score) Sensory and motor block characteristics Haemodynamic parameters of mother Foetal heart rate Duration of 2nd stage of labour Mode of delivery Apgar scores Adverse effects Timepoint: Till delivery of baby

Countries

India

Contacts

Public ContactDr Amrit Kaur
drsmitra12@yahoo.com9646121521

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026