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induction of general anesthesia with two infusion techniques compared with standard technique

A Comparative Study of Two Infusion Doses of Etomidate for Induction Vs. Standard Induction Dose of Etomidate - EIIGA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/04/006879
Enrollment
90
Registered
2016-04-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- PATIENTS UNDERGOING SURGERY UNDER GENERAL ANESTHESIA

Interventions

Intervention1: etomidate drug: three groups E1- Etomidate 50mcg/kg/min via infusion pump till induction E2-Etomidate 25 mcg/kg/min via infusion pump till induction E3-Etomidate 0.2mg/kg manual bolus d

Sponsors

Dean Research JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: AMERICAN PHYSICAL STATUS CLASSIFICATION 1 & 2

Exclusion criteria

Exclusion criteria: Pregnant / Breast feeder The mentally ill Drug abuser Alcohol intoxication Patients on steroids If the infusion dose exceeds the standard bolus dose of 0.2mg/kg

Design outcomes

Primary

MeasureTime frame
To compare the total dose of etomidate required for induction with 50mcg/kg/min infusion and 25mcg/kg/min infusion with standard dose 0.2mg/kg of EtomidateTimepoint: our time points are 1) Time required for loss of eye lash reflex 2) Time required to reach entropy value of 50—

Secondary

MeasureTime frame
To assess and compare the hemodynamic parameters in between different treatment regimens. To assess and compare the time required for induction in different treatment regimensTimepoint: SAMPLING FOR CORTISOL AT BASELINE, 6HRS, 12 HRS, 24HRS, 48HRS—

Countries

India

Contacts

Public ContactDr Rajiv G

JIPMER

munaganuri1975@yahoo.co.in9786184626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 3, 2026