To compare the effect and side effects of Adapalene 0.1%-benzoyl peroxide 2.5% combination gel with adapalene 0.1% gel monotherapy and benzoyl peroxide 2.5% gel monotherapy in treatment of acne vulgaris in Indian patients.

A comparative study of benzoyl peroxide 2.5% gel, Adapalene 0.1% gel and their combination in treatment of acne vulgaris.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/04/006875

Enrollment

Registered

2016-04-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- acne vulgaris

Interventions

Intervention1: adapalene 0.1%- benzoyl peroxide 2.5% combination gel: adapalene 0.1%-benzoyl peroxide 2.5% combination gel applied on face in evening daily for 12 week Control Intervention1: adapalen

Eligibility

Inclusion criteria

Inclusion criteria: grade 2, 3 and 4 on the investigator global assessment scale for acne vulgaris

Exclusion criteria

Exclusion criteria: Patients with grade 5 on investigator global assessment scale for acne, acne conglobata, acne fulminant, secondary acne, pregnant female, female with irregular menstruation, hirsutism and on oral contraceptive or other drugs with possible effects on hormonal level were excluded from study

Design outcomes

Primary

Measure	Time frame
suceess rate( percentage of patients raetd clear or almost clear) on investigator grading for acne scale, mean percent change in total, inflammatory and non inflammatory acne lesionsTimepoint: at week 1,2,4,8 and 12	—

Secondary

Measure	Time frame
signs of tolarability i. e. dryness, stinging and burning, erythema and scalingTimepoint: at week 1,2,4,8 and 12	—

Countries

India

Contacts

Public ContactDr Sugat Jawade

Jawaharlal Nehru Medical College

drsugat09@gmail.com9730974147

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026