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Effectiveness of transcranial direct current stimulation (tDCS) treatment in Obsessive Compulsive Disorder.

A double blind randomised sham controlled study to examine clinical and neuro-cognitive benefits of transcranial direct current stimulation (tDCS) in Obsessive compulsive disorder(OCD)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/04/006837
Enrollment
35
Registered
2016-04-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Obsessive Compulsive Disorder(OCD)

Interventions

Intervention1: Transcranial Direct Current Stimulation (tDCS): Is a non-invasive neuromodulatory brain stimulation technique that delivers low intensity, direct current to cortical areas facilitating
cathode would be placed over the right supra-orbital area. For the true tDCS condition, the stimulation would be done with 2mA 20-minute twice daily sessions separated by atleast 3-hours for 5 days. C

Sponsors

Department of Psychiatry National Institute of Mental Health and Neurosciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Diagnosis of Obsessive Compulsive Disorder (OCD)as per DSM-V criteria (Diagnostic and Statistical Manual for Mental Disorders, American Psychiatric Association, 2013) 2)If the participants are on medications, they would need to be on stable dose of SSRI for atleast 3 months 3)Clinically Significant OCD as evidenced by a cut-off YBOCS severity score of >=16 Age range: 18 â?? 45 years; 6) Both sexes; 7) Right Handedness and 8) Written informed consent.

Exclusion criteria

Exclusion criteria: 1) Features suggestive of psychiatric emergency (for example: suicidal risk, aggression, excitement, catatonia, prolonged nutritional deprivation or any other status requiring intensive clinical care), 2) Any contraindication to tDCS procedure â?? (i) metallic implants in the head, (ii) implanted brain medical devices, (iii) local lesion or injury in the scalp / head, 3) Co-morbid psychiatric diagnoses such as psychosis, bipolar disorder, substance dependence (including nicotine dependence) 4) Mental retardation, neurological disorders and other organic brain disorders 5) Left Handedness.

Design outcomes

Primary

MeasureTime frame
Degree(Severity) of Obsessive and compulsive symptoms Timepoint: Daily before next tDCS sessions

Secondary

MeasureTime frame
CognitionTimepoint: Twice. Before intervention and after intervention

Countries

India

Contacts

Public ContactDr Jhanardhanan

NIMHANS (National Institute of Mental Health and Neurosciences)

ycjreddy@gmail.com9480829472

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 4, 2026