Health Condition 1: null- Patient with biopsy proven cases of oral leukoplakia
Conditions
Interventions
Intervention1: lycopene,cryotherapy: In group A Lycopene preparation will be prescribed in the dosage of 4 mg twice daily for 3 month, In group B Cryotherapy was done according to standard procedure
I
Sponsors
All India Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: All healthy male and female between 15-60 years having oral leukoplakia (biopsy proven) reporting to department of oral and maxillofacial surgery , CDER AIIMS 2. Patients having size of primary lesion more than 1 cm. 3. Patient having history of tobacco chewing/smoking.
Exclusion criteria
Exclusion criteria: 1. Patient having white lesion with negative history of tobacco use. 2. Patients with lesion of size less than 1 cm. 3. Patients with lesion associated with ulcero-proliferative growth or suspicious of squamous cell carcinoma. 4. Patients who are nursing or pregnant. 5. Patients with uncontrolled systemic disease. 6. Patient who are allergic to tomato and food products containing tomato extracts. 7. Patient not willing to quit the adverse habit. 8. Patient refuses to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare clinical response (reduction in size of leukoplakia patch) after lycopene therapy and cryotherapy in the management of oral leukoplakia.Timepoint: after 1 month and 3 month | — |
Secondary
| Measure | Time frame |
|---|---|
| To see for the presence of any new localization/recurrence after therapyTimepoint: evaluation to be done after 3 month and 6 months | — |
Countries
India
Contacts
Public ContactDr Gaurav Jain
AIIMS (Autonomous)
Outcome results
None listed