â??COMPARISON OF DEXMEDETOMIDINE AND CLONIDINE IN ADDITION WITH ROPIVACAINE IN BRACHIAL PLEXUS BLOCK FOR UPPER LIMB ORTHOPEDIC SURGERIESâ??.

â??COMPARISON OF DEXMEDETOMIDINE AND CLONIDINE AS AN ADJUVANT TO ROPIVACAINE IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK FOR UPPER LIMB ORTHOPEDIC SURGERIES: A PROSPECTIVE, RANDOMIZED, DOUBLE BLIND STUDY.â??

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/04/006796

Enrollment

100

Registered

2016-04-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- UPPER LIMB FRACTURES UNDERGOING FOR ORTHOPEDIC SURGERIES

Interventions

Intervention1: ROPIVACAINE,DEXMEDETOMIDINE: DOSE-ROPIVACAINE-30 ML DEXMEDETOMIDINE 1 mg/kg FREQUENCY-SINGLE TIME ROUTE- SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK DURATION-24 HOURS AFTER BLOCK Interv

Eligibility

Inclusion criteria

Inclusion criteria: 1)Informed written consent for participation in study. 2)Age: 18 to 50 years. 3)Gender: Either gender. 4)Patients scheduled for elective upper limb orthopedic surgery 5)ASA physical status I and II. 6)BMI less than or equal to 25kg/m2

Exclusion criteria

Exclusion criteria: 1)Patients refusing consent. 2)Contraindications to regional anesthesia. Previous nerve injury. History of drug dependence/abuse. History of drug allergy. Patients taking analgesics and sedatives. Patients on anticoagulants. History of bleeding disorders. Psychiatric illness. Uncooperative patients. 3)Any major systemic illness like hypertension, heart block etc. 4)Antenatal females and lactating mother. 5)Inadequate effect requiring supplementation. 6)Emergency surgery. 7)ASA physical status III and above.

Design outcomes

Primary

Measure	Time frame
1.Onset, peak and duration of sensory blockade. 2.Onset, peak and duration of motor blockade. 3.Duration of effective post-operative analgesia. 4.Total dose and frequency of rescue analgesics required in 24 hours. 5.Ramsey Sedation score. Timepoint: baseline and than 1 min,3 min,5 min,10 min,15 min,30 min, 1 hour,2 hour, 3 hour, 4 hour and every 2 hourly till 24 hours after brachial block	—

Secondary

Measure	Time frame
1.Effects on hemodynamic variables Heart Rate, Mean Arterial Blood and peripheral oxygen saturation. Timepoint: baseline and than 1 min,3 min,5 min,10 min,15 min,30 min, 1 hour,2 hour, 3 hour, 4 hour and every 2 hourly till 24 hours after brachial block;Complications if any.Timepoint: intra operatively and post operatively till 24 hours	—

Countries

India

Contacts

Public ContactDR KOMAL SHAH

GOVERNMENT MEDICAL COLLEGE AND SIR TAKHTSINHJI HOSPITAL BHAVNAGAR.

shah.Komal@rediff.com09427215252

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026