Health Condition 1: null- Patients with hepatobiliary malignancies with insufficient liver volumes before liver resection
Conditions
Interventions
Intervention1: Portal vein embolisation: The outcoms of portal vein embolisation will be studied.
Control Intervention1: No comparator group.: The outcomes of patients undergoing portal vein embolisat
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with resectable hepatobiliary malignancies requiring liver resection but with insufficient FLR. 2. Patients willing to undergo the procedure.
Exclusion criteria
Exclusion criteria: Patients with contraindications for PVE (Overt clinical portal hypertension -thrombocytopenia, oesophageal varices, splenomegaly, tumour invading the portal vein, extrahepatic metastatic disease, uncorrectable coagulopathy, a tumour precluding safe transhepatic access, contraindications to liver resection such as ASA grade IV status).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess the proportion of liver hypertrophy following PVE.Timepoint: 1. To assess the proportion of liver hypertrophy following PVE. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To study the feasibility of PVE in terms of of technical success rate. 2. To study the periprocedural complications associated with PVE. 3. To study the impact of PVE in terms of derangement of liver function tests, progression of the disease in waiting the period, and difficulties encountered during surgery. 4. To study the overall success rate of PVE in terms of percentage of patients who underwent planned hepatic resection. Timepoint: On follow up | — |
Countries
India
Contacts
Public ContactDr Vedavyas Mohapatra
AIIMS
Outcome results
None listed