Health Condition 1: null- Pneumonia Health Condition 2: J189- Pneumonia, unspecified organism
Conditions
Interventions
Intervention1: High Flow Nasal Cannula oxygen administration method: Oxygen will be administered by High flow nasal cannula
Control Intervention1: Simple flow nasal cannula oxygen administration metho
Sponsors
INCLEN Trust International
Eligibility
Inclusion criteria
Inclusion criteria: All consecutive children aged 2months to 5 years admitted to pediatric emergency room with severe pneumonia requiring oxygen therapy would be enrolled in this study after getting informed consent from parents
Exclusion criteria
Exclusion criteria: •Children diagnosed to have chronic lung disease •Any child hospitalized for respiratory illness in last one month period •Children previously diagnosed to have bronchial asthma •Children receiving home mechanical ventilation •Children diagnosed to have preexisting neuromuscular disease •Congenital cardiac malformations or other multiple malformations •Children diagnosed to have empyema at admission to emergency room
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| â??Treatment Failureâ?? in 72 hours of hospitalization would be the primary outcome measure and â??Treatment failure" could include any of following (i) Endotracheal intubation, (ii) Mechanical ventilation, (iii) escalating the respiratory support method (using any modality other than primary intervention method)Timepoint: â??Treatment Failureâ?? in 72 hours of hospitalization would be the primary outcome measure and â??Treatment failure" could include any of following (i) Endotracheal intubation, (ii) Mechanical ventilation, (iii) escalating the respiratory support method (using any modality other than primary intervention method) | — |
Secondary
| Measure | Time frame |
|---|---|
| a.Time to clinical stability in hours [Continuous variable] b.Time to respiratory stability in hours [Continuous variable] c.Fluid balance (ml/kg) at 24 and 48 hours of hospitalization [continuous variable] d.Volume of crystalloid bolus requirement [Continuous variable] e.Mortality (In hospital and in 30 days of discharge) [categorical variable] Timepoint: as specified | — |
Countries
India
Contacts
Public ContactK Sasidaran
Dr Mehtas Childrens Hospital, Chennai
Outcome results
None listed