Health Condition 1: null- Patient had multiple hormone deficiencies, developed after post partum period due to pituitary necrosis
Conditions
Interventions
Intervention1: Oral contraceptive pills
contains estrogen and progesterone: patients were given OCPs for 21 days in a month for 1 year then BMD was compared before and after giving drug
Intervention2:
Sponsors
SGPGIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1.Absent lactation and/or PPH (postpartum hemorrage)and Menstrual disturbances after last delivery 2. Clinical evidence of deficiency of one or more pituitary hormones 3. Documentation of deficiency of at least one pituitary hormone 4. Absence of clinical or radiological feature of pituitary mass lesion
Exclusion criteria
Exclusion criteria: 1. Other etiologies of hypopituitarism 2. Age > 42 years 3. Patients with chronic diseases like uncontrolled diabetes, CAD, CKD, Liver disease and chronic inflammatory disorders 4. Patient with history of thromboembolic disorders 5. Patients with suspected breast, endometrial or cervical cancer 6. Patients on supra-physiological doses of steroids, anti-epileptic drugs and bisphosphonates
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effect on BMD after sex steroid replacement in the follow up patients of Sheehans syndrome Timepoint: 1 year follow up | — |
Secondary
| Measure | Time frame |
|---|---|
| morbidity fracture incidenceTimepoint: 1 year follow up | — |
Countries
India
Contacts
Public ContactDr Purnima Agarwal
Sanjay Gandhi Postgraduate Institute of Medical Sciences
Outcome results
None listed