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Effect of Vitamin C supplementation on Diabetes Mellitus and assessment of salivary vitamin C along with periodontal health.

Evaluation of Glycated Hemoglobin levels in type 2 Diabetes Mellitus and Prediabetes after oral supplementation of vitamin C along with assessment of changes in salivary vitamin C levels and periodntal health : A randomized control clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/03/006764
Enrollment
200
Registered
2016-03-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Diabetics (HbA1c above 6.5%) and Prediabetics (5.7-6.4%)

Interventions

Intervention1: Ascorbic Acid 500mg , Scaling and Root planing: Oral Supplementation of Ascorbic acid 500mg BD for 6 months ,Scaling and root planing at the end of 3 months from start of study Control
prediabetics with HbA1c between 5.7-6.4%.Controls will not be receiving oral supplementation of Vitamin C

Sponsors

Dr H N Santosh
Lead Sponsor
Dr Chaya M David
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients only under oral hypoglycemic agents 2. Hba1c >6.5% for dibetics and 5.7-6.4% for prediabetics 3. Patients with chronic generalized periodontitis

Exclusion criteria

Exclusion criteria: 1. Patients above the age of 60 years and less than 30 years will be excluded . 2. Patients whose are on insulin therapy will be excluded. 3. Patients with type 1 diabetes or Pregnancy induced diabetes will be excluded. 4. Patients with chronic complications of diabetes or any other endocrine disease will be excluded. 5. Patients who have taken supplementation of vitamins in the past 3 months will be excluded . 6. Patients with present history of smoking and alcohol intake will be excluded will be excluded.

Design outcomes

Primary

MeasureTime frame
1. HbA1c(Glycocylated Hemoglobin Levels) 2. Salivary Vitamin C levels 3. Clinical Attachment LevelTimepoint: 0 to 6 months at 3 months interval

Secondary

MeasureTime frame
1. HbA1c(Glycocylated Hemoglobin Levels) 2. Salivary Vitamin C levels 3. Clinical Attachment LevelTimepoint: 0 to 6 months at 3 months interval

Countries

India

Contacts

Public ContactDr H N Santosh

Dayananda Sagar College of Dental Sciences and Hospital

chaya_alfred@yahoo.com9844253310

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 26, 2026