Association between joint pain and gum diseases

Ã¢â?¬Å?Effect of Non-Surgical Periodontal Therapy on Chronic Periodontitis and Rheumatoid Arthritis and a correlation of Anti-Citrullinated Protein Antibody (ACPA) levels in South Indian PopulationÃ¢â?¬? - RA-CP

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/03/006751

Enrollment

Registered

2016-03-21

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: null- Rheumatoid arthritis patients treated as Out patients in Department of Rheumatology, Madras Medical College suffering from chronic periodontitis Health Condition 3: M056- Rheumatoid arthritis with involvement of other organs and systems Health Condition 4: M056- Rheumatoid arthritis with involvement of other organs and systems Health Condition 5: M059- Rheumatoid arthritis with rheumatoid factor, unspecified

Interventions

Intervention1: effect of non-surgical periodontal treatment in patients with Rheumatoid arthritis and periodontitis: rheumatoid arthritis patients already taking medications from Department of Rheumat

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willing for voluntary participation and have signed informed consent. 2. Age group: 30- 65 years old. 3. Either sex. 4. under medication for rheumatoid arthritis Patients taking DMARD- disease modifying anti-rheumatic drugs for atleast 6 months 5. Having atleast 8 teeth 6. Periodontal disease (at least 1 site with PPD >4mm, clinical attachment loss > 3mm) 7. Available for the study for a period of 6 months

Exclusion criteria

Exclusion criteria: 1. Recent history of hospitalization. 2. Acute generalized infection/chronic systemic infection necessitating chronic antibiotic intake. 3. Acute oral infection or condition necessitating extraction/suspected premalignant lesions/conditions in the mouth 4. Patients with uncontrolled, Hypertension, Cardiovascular, Respiratory, Renal disorder. 5. Patients in need of any change or increase in dosage of DMARD drugs. 6. Patients with diabetes mellitus, psoriatic arthritis, ankylosing spondylitis 7. Current smokers 8. Pregnancy or lactation at the time of inclusion.

Design outcomes

Primary

Measure	Time frame
Change in DAS 28 Disease Activity Score in Rheumatoid patients with Chronic periodontitisTimepoint: 3 months	—

Secondary

Measure	Time frame
Quality of Life Index (QOLI) in rheumatoid arthritis patientsTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDrSRajeswari

jaishreekt@gmail.com9498031450

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026