Randomized control study comparing various modalities of thromboprophylaxis used after total knee and hip arthroplasty

Prospective study of role of thromboembolic prophylaxis with low molecular weight heparin or Aspirin plus intermittent compression devices undergoing Total Hip and Knee Arthroplasty

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/03/006736

Enrollment

300

Registered

2016-03-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients undergoing knee and hip arthoplasty

Interventions

Intervention1: low molecular weight heparin 0.4ml suncutaneous HS for 5 days, aspirin 325 mg PO bd for 6 weeks ,intermittent compression device for 3 days.: low molecular weight heparin versus Aspirin

Eligibility

Inclusion criteria

Inclusion criteria: Indian patients undergoing hip and knee arthroplasty

Exclusion criteria

Exclusion criteria: patients aged 90 years, patients with coagulation or bleeding disorders, hypersensitivity to aspirin or low molecular weight heparin, Heparin induced thrombocytopenia, history of thromboembolic disease/ chronic venous insufficiency, ocular or neurosurgical procedure during last 3 month, active peptic ulcer disease, severe renal insufficiency, systolic hypertension >200 mm Hg, pulmonary tuberculosis, a solid malignancy tumor, active Liver disease, peripheral vascular disease , and who refused to give consent.

Design outcomes

Primary

Measure	Time frame
Deep vein thrombosis after arthroplastyTimepoint: within 3 months of surgery	—

Secondary

Measure	Time frame
PETimepoint: 3 MONTHS	—

Countries

India

Contacts

Public ContactSushil Paudel

All India Institute of Medical Sciences

csyadavortho@gmail.com9868479933

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026