evaluating the effects of propofol in brain using advanced imaging

Evaluation of the effects of 1% propofol on the cortical and sub-cortical areas of the brain using functional magnetic resonance imaging technique

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/03/006720

Enrollment

Registered

2016-03-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- chronic back pain

Interventions

Intervention1: Sedation: Propofol will be administered as sedation during MRI study Intervention2: Propofol: propofol will be administered and pre and post administration changes in the fMRI BOLD sign

Eligibility

Inclusion criteria

Inclusion criteria: patients with chronic back pain

Exclusion criteria

Exclusion criteria: structural brain pathology

Design outcomes

Primary

Measure	Time frame
BOLD signal changes on fMRITimepoint: pre and post propofol, 6 minutes	—

Secondary

Measure	Time frame
Cardiorespiratory changesTimepoint: Every 5 minutes from baseline till patient is awake	—

Countries

India

Contacts

Public ContactSriganesh K

NIMHANS

drsri23@rediffmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026