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To assess the effect of three different doses of oral gabapentin drug for pain relief in patient undergoing inguinal herniorraphy under spinal anaesthesia

Role of preemptive gabapentin on postoperative analgesia and opioid consumption following infra-umbilical surgeries (inguinal herniorraphy) under subarachnoid block in Indian population - a randomized, placebo controlled, double blind study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/03/006705
Enrollment
120
Registered
2016-03-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- 120 American Society of Anesthesiologists physical status I and II, male patients scheduled for inguinal herniorraphy

Interventions

Intervention1: gabapentin 400 mg (Group B): Patients were divided into four groups of 30 patients each to receive placebo (Group B) GABAPENTIN 400 MG capsule administered orally 2 hr before surgery. I

Sponsors

St Stephens Hospital Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 120 American Society of Anesthesiologists physical status I and II, adult male patients scheduled for inguinal herniorraphy surgery

Exclusion criteria

Exclusion criteria: refusal to participate, failure of sab arachnoid block, body weight ±20% of the ideal body weight, age more than 70 years or, less than 18 years, history of drug or alcohol abuse, history of hypersensitivity to any drug, history of peptic ulcer or of bleeding diathesis or taking antacids, uncontrolled concomitant medical diseases (diabetes mellitus, hypertension), acute exacerbation of bronchial asthma, impaired kidney or liver functions, spondylolisthesis to be treated with spinal plating or additional pathology of the spine, ingestion of analgesics, antidepressant or sedatives other than those used in this study (if any) within 24 hours before scheduled surgery.

Design outcomes

Primary

MeasureTime frame
to evaluate the effects of three different doses of preemptive gabapentin on the acute post-inguinal herniorraphy painTimepoint: postoperative 00 hours to 24 hours—

Secondary

MeasureTime frame
and the side effects/adverse effect associated with different doses of gabapentin in recovery period.Timepoint: postoperative 00 hours to 24 hours;postoperative opioid requirement during the initial 24 hoursTimepoint: postoperative 00 hours to 24 hours;time for first rescue analgesic requirement in postoperative periodTimepoint: postoperative day 1: 00 hours to 24 hours—

Countries

India

Contacts

Public ContactDr Grace Cherian

St. Stephens Hospital, New Delhi

cherian.grace@rediffmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026