Health Condition 1: null- Type 2 dibetes mellitus patients
Conditions
Interventions
Intervention1: vitamin D3 60,000 I.U oral: oral vitamin D3 60,000 I.U weekly for 8 weeks will be given for vitamin D deficient patients and they will be followed up for 2 months and their vitamin D le
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with type 2 diabetes mellitus for past 10 years or less and on stable treatment for past 3 months, and taking metformin or sulphonylurea or both.
Exclusion criteria
Exclusion criteria: 1)Liver dysfunction (AST,ALT > 1.5 times the upper limit of normal) 2)Renal dysfunction (Serum creatinine, blood urea > 1.5 times the upper limit of normal) 3)Patient with concurrent illnesses other than hypertension 4)Patients taking enzyme inducers or inhibitors 5)Patients already taking vitamin D supplements 6)Pregnant and lactating woman 7)Severe uncontrolled hypertension ( >160/90 mm Hg) 8)Smokers 9)Patients who had participated in other trials within last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in carotid femoral pulse wave velocityTimepoint: Change in carotid femoral pulse wave velocity after 8 weeks of vitamin D supplementation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in brachial artery pulse wave velocity, arterial stiffness index, serum malondialdehyde levels and total anti oxidant status .Timepoint: After 8 weeks of vitamin d supplementation | — |
Countries
India
Contacts
Public ContactDr NishanthiA
JIPMER
Outcome results
None listed